Soluble guanylate cyclase and NO/cGMP signalling in vascular disease
NO-independent stimulators and activators of soluble guanylate cyclase:
Cellular cyclic GMP is increased by activation of soluble guanylate cyclase
Soluble and Particulate Guanylyl Cyclase
The heterodimeric soluble guanylyl cyclase consists of a heme domain,
Marletta Lab - Soluble Guanylate Cyclase
Catalysis of cyclic GMP synthesis by soluble guanylyl cyclase.
Figure 1: Schematic presentation of the soluble guanylate cyclase screening
Soluble guanylate cyclase (sGC) catalyzes the conversion of GTP to the
Soluble guanylyl cyclase (sGC) is a cytosolic signaling enzyme closely
b) soluble guanylate cyclase
of the NO binding heme domain of the soluble guanylyl cyclase receptor.
NO-independent stimulators and activators of soluble guanylate cyclase:
GTP (Guanosine 5`-triphosphate), sGC (Soluble guanylate cyclase).
Tonic and acute nitric oxide signaling through soluble guanylate cyclase is
GTP (Guanosine 5`-triphosphate), sGC (Soluble guanylate cyclase).
Inhibition of soluble guanylate cyclase prevents the AQP1 conductance response to SNP
Revisiting the kinetics of nitric oxide (NO) binding to soluble guanylate
nuclear factor-κB; NO, nitric oxide; sGC, soluble guanylate cyclase.
Effect of Soluble Guanylate Cyclase-Specific Inhibitor on Tissue Relaxation
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